2’-氰基-4-甲醛基联苯合成路线 （共 19 条）
反应条件
1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane; acetic acid in water; chlorobenzene T=93°C; 9 h;
参考文献
JP2005/82496 A, ;
Page/Page column 12 ;
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethanol; toluene T=100°C; Suzuki cross-coupling; 5 h;
参考文献
Organic Letters, , vol. 3, # 10 p. 1435 - 1437
反应条件
1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane; water; acetic acid in chlorobenzene T=90°C; 11 h;
参考文献
JP2005/82496 A, ;
Page/Page column 13 ;
反应条件
copper carbonate hydroxide; potassium carbonate; triphenylphosphine; 1,10-phenanthroline in quinoline T=170°C; 24 h;
参考文献
Journal of Organic Chemistry, , vol. 72, # 19 p. 7473 - 7476
反应条件
bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran T=160°C; Negishi reaction; 0.0166667 h; microwave irradiation;
参考文献
Synlett, , # 12 p. 1893 - 1896
反应条件
sodium hydrogencarbonate in dimethyl sulfoxide
反应条件
dimethyl sulfoxide; triethylamine in hexane; dichloromethane
参考文献
US5399578 A1, ;
US 5399578 A
反应条件
potassium carbonate in ethanol; water T=50°C; Suzuki coupling; 19 h;
参考文献
Advanced Synthesis and Catalysis, , vol. 353, # 11-12 p. 2119 - 2130
反应条件
1: 72 percent / acetic anhydride; pyridine 2: 50 percent / basic copper(II) carbonate; potassium carbonate; triphenylphosphine / palladium(II) bromide; 1,10-phenanthroline / quinoline / 24 h / 170 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 72, # 19 p. 7473 - 7476
反应条件
1: copper(II) oxide; potassium carbonate; potassium fluoride / palladium(II) bromide; 1,10-phenanthroline / quinoline / 24 h / 170 °C 2: 167.9 mg / aq. HCl / 2 h / 50 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 72, # 19 p. 7473 - 7476
