6,7-二甲氧基-3,4-二氢-2H-1-萘酮合成路线 （共 42 条）
反应条件
[TMAH][Al2Cl7] in dichloromethane Heating;
参考文献
N.V. Organon
Patent: US2011/28451 A1, 2011 ;
US 20110028451 A1
参考文献
Beugelmans, Rene; Chastanet, Jacqueline; Ginsburg, Helene; Quintero-Cortes, Leticia; Roussi, Georges
Journal of Organic Chemistry, 1985 , vol. 50, # 24 p. 4933 - 4938
反应条件
oxygen in tert-butyl alcohol
参考文献
Crosby, Ian T.; Bourke, David G.; Jones, Eric D.; De Bruyn, Paula J.; Rhodes, David; Vandegraaff, Nick; Cox, Susan; Coates, Jonathan A.V.; Robertson, Alan D.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 17 p. 6442 - 6450
反应条件
1: 1.) ZnI2; 2.) POCl3 / 2.) pyridine 2: 68 percent / n-Bu4NHSO4, NaOH, H2O2 3: 87 percent / 3N HCl / Heating View Scheme
参考文献
Thrift,R.I.
Journal of the Chemical Society [Section] C: Organic, 1967 , p. 288 - 293
反应条件
1: benzene; diethyl ether / Erhitzen des Reaktionsprodukts
2: peroxybenzoic acid
3: benzene; sodium methylate; methanol
View Scheme
参考文献
Howell; Taylor
Journal of the Chemical Society, 1958 , p. 1248,1251
反应条件
1: 68 percent / NH3(liq.), t-C4H9OK, air / Irradiation
2: 68 percent / 30percent Pd/C / 4 h / 250 °C
View Scheme
参考文献
Beugelmans, Rene; Chastanet, Jacqueline; Ginsburg, Helene; Quintero-Cortes, Leticia; Roussi, Georges
Journal of Organic Chemistry, 1985 , vol. 50, # 24 p. 4933 - 4938
反应条件
1: 1.) Mg / 1.) ether, 2.) a) RT, 6 h, b) reflux, 1 h
2: 80 percent / H2 / PtO2 / ethanol / 8 h / 2660 Torr
View Scheme
参考文献
Bandaranayake, Wickramasinghe M.; Riggs, Noel V.
Australian Journal of Chemistry, 1981 , vol. 34, # 1 p. 115 - 129
反应条件
1: zinc(II) iodide / benzene / 12 h / 60 °C / Inert atmosphere
2: trifluoroacetic acid / dichloromethane / 2 h / 0 - 20 °C
View Scheme
参考文献
CORNELL UNIVERSITY; COFERON, INC.; PURDUE RESEARCH FOUNDATION
Patent: US2012/295874 A1, 2012 ;
US 20120295874 A1
反应条件
hydrogenchloride
1.) toluene, -15 deg C, 80 min., 2.) toluene, MeOH, 1h; Yield given. Multistep reaction;
参考文献
Cannon; Perez; Long; Ilhan
Journal of Medicinal Chemistry, 1983 , vol. 26, # 6 p. 813 - 816
反应条件
zinc(II) iodide; trichlorophosphate
2.) pyridine; Yield given. Multistep reaction;
参考文献
Pryde, David C.; Henry, Steven S.; Meyers
Tetrahedron Letters, 1996 , vol. 37, # 19 p. 3243 - 3246
