6-氨基-5,6,7,8-四氢-2,3-萘二醇溴酸盐合成路线 （共 14 条）
反应条件
hydrogen bromide in water Heating;
参考文献
Goeksu, Sueleyman; Kazaz, Cavit; Suetbeyaz, Yasar; Secen, Hasan
Helvetica Chimica Acta, 2003 , vol. 86, # 10 p. 3310 - 3313
反应条件
1.1: (PhO)2P(O)N3; Et3N / benzene / Heating 1.2: 86 percent / benzene / Heating 2.1: 95 percent / H2 / Pd-C / methanol; CHCl3 / 24 h / 20 °C 3.1: 80 percent / HBr / H2O / Heating View Scheme
参考文献
Narula, Anubhav P.S.; Schuster, David I.
Tetrahedron Letters, 1981 , vol. 22, # 38 p. 3707 - 3710
反应条件
1: 95 percent / H2 / Pd-C / methanol; CHCl3 / 24 h / 20 °C 2: 80 percent / HBr / H2O / Heating View Scheme
参考文献
Narula, Anubhav P.S.; Schuster, David I.
Tetrahedron Letters, 1981 , vol. 22, # 38 p. 3707 - 3710
反应条件
1: 1.) n-BuLi / 1.) THF, -100 deg C, 1 h 2.) -100 deg C, 2h and warm up to room temp. 2: 98 percent / 20percent aq. NaOH / methanol / 5 h / Heating 3: Diphenylphosphoroazidate, Et3N / benzene / 2 h / Heating 4: 24 h / Heating 5: 86 percent / Hydrogen, HCl / 5percent Pd/C / methanol 6: 48percent HBr / Heating View Scheme
参考文献
Narula, Anubhav P.S.; Schuster, David I.
Tetrahedron Letters, 1981 , vol. 22, # 38 p. 3707 - 3710
反应条件
1: NBS, Ph3P / benzene / 1.5 h / Heating 2: 1.) n-BuLi / 1.) THF, -100 deg C, 1 h 2.) -100 deg C, 2h and warm up to room temp. 3: 98 percent / 20percent aq. NaOH / methanol / 5 h / Heating 4: Diphenylphosphoroazidate, Et3N / benzene / 2 h / Heating 5: 24 h / Heating 6: 86 percent / Hydrogen, HCl / 5percent Pd/C / methanol 7: 48percent HBr / Heating View Scheme
参考文献
Narula, Anubhav P.S.; Schuster, David I.
Tetrahedron Letters, 1981 , vol. 22, # 38 p. 3707 - 3710
反应条件
1: 98 percent / 20percent aq. NaOH / methanol / 5 h / Heating 2: Diphenylphosphoroazidate, Et3N / benzene / 2 h / Heating 3: 24 h / Heating 4: 86 percent / Hydrogen, HCl / 5percent Pd/C / methanol 5: 48percent HBr / Heating View Scheme
参考文献
Narula, Anubhav P.S.; Schuster, David I.
Tetrahedron Letters, 1981 , vol. 22, # 38 p. 3707 - 3710
反应条件
1: Br2 / acetic acid 2: NBS, Ph3P / benzene / 1.5 h / Heating 3: 1.) n-BuLi / 1.) THF, -100 deg C, 1 h 2.) -100 deg C, 2h and warm up to room temp. 4: 98 percent / 20percent aq. NaOH / methanol / 5 h / Heating 5: Diphenylphosphoroazidate, Et3N / benzene / 2 h / Heating 6: 24 h / Heating 7: 86 percent / Hydrogen, HCl / 5percent Pd/C / methanol 8: 48percent HBr / Heating View Scheme
参考文献
Narula, Anubhav P.S.; Schuster, David I.
Tetrahedron Letters, 1981 , vol. 22, # 38 p. 3707 - 3710
反应条件
1.1: 88 percent / AlCl3 / 1,2-dichloro-ethane / 13 h / 0 °C 2.1: 90 percent / Br2 / tetrahydrofuran; H2O / 8 h / 20 °C 3.1: 90 percent / Na; NH3 / 2 h / -70 °C 4.1: (PhO)2P(O)N3; Et3N / benzene / Heating 4.2: 86 percent / benzene / Heating 5.1: 95 percent / H2 / Pd-C / methanol; CHCl3 / 24 h / 20 °C 6.1: 80 percent / HBr / H2O / Heating View Scheme
参考文献
Goeksu, Sueleyman; Kazaz, Cavit; Suetbeyaz, Yasar; Secen, Hasan
Helvetica Chimica Acta, 2003 , vol. 86, # 10 p. 3310 - 3313
反应条件
1.1: 90 percent / Na; NH3 / 2 h / -70 °C 2.1: (PhO)2P(O)N3; Et3N / benzene / Heating 2.2: 86 percent / benzene / Heating 3.1: 95 percent / H2 / Pd-C / methanol; CHCl3 / 24 h / 20 °C 4.1: 80 percent / HBr / H2O / Heating View Scheme
参考文献
Goeksu, Sueleyman; Kazaz, Cavit; Suetbeyaz, Yasar; Secen, Hasan
Helvetica Chimica Acta, 2003 , vol. 86, # 10 p. 3310 - 3313
反应条件
1.1: 94 percent / K2CO3 / acetone / 15 h / Heating 2.1: 88 percent / AlCl3 / 1,2-dichloro-ethane / 13 h / 0 °C 3.1: 90 percent / Br2 / tetrahydrofuran; H2O / 8 h / 20 °C 4.1: 90 percent / Na; NH3 / 2 h / -70 °C 5.1: (PhO)2P(O)N3; Et3N / benzene / Heating 5.2: 86 percent / benzene / Heating 6.1: 95 percent / H2 / Pd-C / methanol; CHCl3 / 24 h / 20 °C 7.1: 80 percent / HBr / H2O / Heating View Scheme
参考文献
Goeksu, Sueleyman; Kazaz, Cavit; Suetbeyaz, Yasar; Secen, Hasan
Helvetica Chimica Acta, 2003 , vol. 86, # 10 p. 3310 - 3313
