3,4-二氢-2H-4-苯并噁嗪-2-羧酰胺合成路线 （共 7 条）
反应条件
in sulfuric acid T=100°C; 0.25 h;
参考文献
Butler; Chapleo; Myers; Welbourn
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 1 p. 177 - 181
反应条件
ammonia in ethanol 14 h;
参考文献
Bourlot, Anne-Sophie; Sanchez, Isabel; Dureng, Georges; Guillaumet, Gerald; Massingham, Roy; Monteil, Andre; Winslow, Eileen; Pujol, M. Dolors; Merour, Jean-Yves
Journal of Medicinal Chemistry, 1998 , vol. 41, # 17 p. 3142 - 3158
反应条件
1: NH3 / ethanol / 14 h 2: 22 percent / aq. H2SO4 / 0.25 h / 100 °C View Scheme
参考文献
Butler; Chapleo; Myers; Welbourn
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 1 p. 177 - 181
反应条件
ammonium hydroxide in ethanol Ambient temperature;
参考文献
Predvoditeleva,G.S.; Shchukina,M.N.
J. Gen. Chem. USSR (Engl. Transl.), 1963 , vol. 33, p. 145 - 150,138 - 142
反应条件
1: K2CO3 / acetone / Heating 2: aq. NH3 / ethanol / Ambient temperature View Scheme
参考文献
Predvoditeleva,G.S.; Shchukina,M.N.
J. Gen. Chem. USSR (Engl. Transl.), 1963 , vol. 33, p. 145 - 150,138 - 142
反应条件
trichlorophosphate in pyridine 1) 0 - 5 deg C, 1 h, 2) RT, 3 h;
参考文献
Butler; Chapleo; Myers; Welbourn
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 1 p. 177 - 181
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=45°C; 36 h;
参考文献
Bourlot, Anne-Sophie; Sanchez, Isabel; Dureng, Georges; Guillaumet, Gerald; Massingham, Roy; Monteil, Andre; Winslow, Eileen; Pujol, M. Dolors; Merour, Jean-Yves
Journal of Medicinal Chemistry, 1998 , vol. 41, # 17 p. 3142 - 3158
