1-Boc-吡咯-2-硼酸合成路线 （共 13 条）
反应条件
sodium hydroxide in tetrahydrofuran; water T=23°C; 0.333333 h;
参考文献
Knapp, David M.; Gillis, Eric P.; Burke, Martin D.
Journal of the American Chemical Society, 2009 , vol. 131, p. 6961 - 6963
反应条件
1: With 2,2,6,6-tetramethyl-piperidine; n-butyllithium in tetrahydrofuran; hexane T=-78°C; 2 h; 2: With boric acid trimethyl ester in tetrahydrofuran; hexane T=20°C; Further stages.;
参考文献
Haynes, Stuart W.; Sydor, Paulina K.; Stanley, Anna E.; Song, Lijiang; Challis, Gregory L.
Chemical Communications, 2008 , # 16 p. 1865 - 1867
反应条件
2,2,6,6-tetramethylpiperidinyl-lithium in tetrahydrofuran inert atmosphere; -78°C;
参考文献
Gao, Changshou; Lavey, Brian J.; Lo, Chih-Hung L.; Datta, Anita; Wentworth Jr., Paul; Janda, Kim D.
Journal of the American Chemical Society, 1998 , vol. 120, # 10 p. 2211 - 2217
反应条件
1: N-(tert-butyloxycarbonyl)pyrrole With 2,2,6,6-tetramethylpiperidin-4-yl heptanoate; n-butyllithium 2: boric acid trimethyl ester
参考文献
Pawlicki, Milosz; Hurej, Karolina; Szterenberg, Ludmila; Latos-Grazynski, Lechoslaw
Angewandte Chemie - International Edition, 2014 , vol. 53, # 11 p. 2992 - 2996
Angew. Chem., 2014 , vol. 126, # 11 p. 3036 - 3040,5
反应条件
in tetrahydrofuran; hexane
参考文献
Zeneca Limited
Patent: US6265411 B1, 2001 ;
反应条件
in not given hydrolysis of appropriate N-methyliminodiacetic acid boronate;
参考文献
Journal of the American Chemical Society, , vol. 131, p. 6961 - 6963
反应条件
methanol; tetrakis(triphenylphosphine) palladium(0); caesium carbonate in toluene Suzuki coupling; 24 h; RefluxInert atmosphere;
参考文献
Journal of Heterocyclic Chemistry, , vol. 48, # 6 p. 1329 - 1335
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethylene glycol dimethyl ether; water T=20 - 45°C; 2 h; Inert atmosphere;
参考文献
Maeda, Hiromitsu; Kinoshita, Kota; Naritani, Kazumasa; Bando, Yuya
Chemical Communications, 2011 , vol. 47, # 29 p. 8241 - 8243
反应条件
N,N-dimethyl-N-(4'-methylphenyl)amine N-oxide in dichloromethane T=20°C; 4 h;
参考文献
Zhu, Chen; Wang, Rui; Falck
Organic Letters, 2012 , vol. 14, # 13 p. 3494 - 3497
反应条件
catalyst: PtO2 in ethyl acetate inert atmosphere; hydrogenation (50 psi, 8 h) of stirred suspn. of B-compd. and Adam's catalyst, reaction mixt. filtration (Celite), pptn. on filtrat concn. (vac.); elem. anal.;
参考文献
Gao, Changshou; Lavey, Brian J.; Lo, Chih-Hung L.; Datta, Anita; Wentworth Jr., Paul; Janda, Kim D.
Journal of the American Chemical Society, 1998 , vol. 120, # 10 p. 2211 - 2217
