(S)-6-氯甲基-5,6-二氢吡喃-2-酮合成路线 (共 3 条)
反应条件
1: With sodium tetrahydroborate in ethanol
T=0°C;
2: With toluene-4-sulfonic acid in toluene
T=20 - 120°C; 18 h;
参考文献
Job; Wolberg; Mueller; Enders
Synlett, 2001 , # 11 p. 1796 - 1798
反应条件
toluene-4-sulfonic acid in toluene
Heating;
参考文献
Wolberg, Michael; Hummel, Werner; Wandrey, Christian; Mueller, Michael
Angewandte Chemie - International Edition, 2000 , vol. 39, # 23 p. 4306 - 4308
反应条件
1: 72 percent / NADPH; recBADH
2: 100 percent / NaBH4 / ethanol / 0 °C
3: TsOH / toluene / Heating
View Scheme
参考文献
Wolberg, Michael; Hummel, Werner; Wandrey, Christian; Mueller, Michael
Angewandte Chemie - International Edition, 2000 , vol. 39, # 23 p. 4306 - 4308