1,3-苯二酚单苯甲酸酯合成路线 （共 26 条）
反应条件
1: 93 percent / PPh3; diisopropyl azodicarboxylate / tetrahydrofuran 2: 98 percent / aq. NaOH / methanol View Scheme
参考文献
PFIZER INC.; ASPNES, Gary Erik; DIDIUK, Mary Theresa; GUZMAN-PEREZ, Angel; MAGUIRE, Robert John
Patent: WO2011/158149 A1, 2011 ;
WO 2011/158149 A1
反应条件
1.1: H2SO4; I2 / CHCl3 1.2: BuSnH; AIBN / toluene / Heating 2.1: 90 percent / NaOH / methanol View Scheme
参考文献
Boxhall, Jonathan Y.; Page, Philip C. Bulman; Chan, Yohan; Hayman, Colin M.; Heaney, Harry; McGrath, Matthew J.
Synlett, 2003 , # 7 p. 997 - 1001
反应条件
1: K2CO3 / dimethylformamide / 2 h / 60 °C
2: 289 mg / KOH / methanol / 0.42 h / 20 °C
View Scheme
参考文献
Boxhall, Jonathan Y.; Page, Philip C. Bulman; Chan, Yohan; Hayman, Colin M.; Heaney, Harry; McGrath, Matthew J.
Synlett, 2003 , # 7 p. 997 - 1001
反应条件
1: 93 percent / PPh3; diisopropyl azodicarboxylate / tetrahydrofuran / 4.25 h / 0 - 20 °C
2: 98 percent / aq. NaOH / ethanol / 3 h
View Scheme
参考文献
Boxhall, Jonathan Y.; Page, Philip C. Bulman; Chan, Yohan; Hayman, Colin M.; Heaney, Harry; McGrath, Matthew J.
Synlett, 2003 , # 7 p. 997 - 1001
反应条件
2: aqueous ethanol; sodium dithionite
View Scheme
参考文献
Barton; Linnell; Senior
Journal of the Chemical Society, 1945 , p. 436
反应条件
1: anhydrous chloroform; bromine
2: aqueous NaOH
View Scheme
参考文献
Hodgson; Dyson
Journal of the Chemical Society, 1935 , p. 946
