5-(3,4-亚甲基二氧苯基)-2,4-戊二烯酸合成路线 （共 16 条）
参考文献
Fittig; Mielck
Justus Liebigs Annalen der Chemie, 1869 , vol. 152, p. 52,54
Justus Liebigs Annalen der Chemie, 1874 , vol. 172, p. 140,152
Full Text Show Details
Doebner
Chemische Berichte, 1890 , vol. 23, p. 2378
Chemische Berichte, 1891 , vol. 24, p. 1746
反应条件
4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide
Amidation;
参考文献
Chandrasekhar; Venkat Reddy; Srinivasa Reddy; Ramarao
Tetrahedron Letters, 2000 , vol. 41, # 15 p. 2667 - 2670
反应条件
1: Et3N / CH2Cl2 / 0.5 h / 0 °C
2: 186 mg / CH2Cl2 / 3 h / 0 - 20 °C
View Scheme
参考文献
Koul, Surrinder; Koul, Jawahir L.; Taneja, Subhash C.; Dhar, Kanaya L.; Jamwal, Deshvir S.; Singh, Kuldeep; Reen, Rashmeet K.; Singh, Jaswant
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 1 p. 251 - 268
反应条件
1: 60 percent / diisobutylaluminum hydride / tetrahydrofuran / 1 h / -10 °C
2: 93 percent / MnO2 / tetrahydrofuran / 3 h / Heating
View Scheme
参考文献
Qu, Huan; Yu, Xiang; Zhi, Xiaoyan; Lv, Min; Xu, Hui
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 20 p. 5552 - 5557
反应条件
1: piperic acid With thionyl chloride in dichloromethane
1 h; Reflux;
2: isobutylamine in dichloromethane
1 h;
参考文献
Sangwan, Payare L.; Koul, Jawahir L.; Koul, Surrinder; Reddy, Mallepally V.; Thota, Niranjan; Khan, Inshad A.; Kumar, Ashwani; Kalia, Nitin P.; Qazi, Ghulam N.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 22 p. 9847 - 9857
反应条件
1: Et3N / CH2Cl2 / 0.5 h / 0 °C
2: 120 mg / CH2Cl2 / 3 h / 0 - 20 °C
View Scheme
参考文献
De Paula, Vanderlucia F.; De A Barbosa, Luiz C.; Demuner, Antonio J.; Pilo-Veloso, Dorila; Picanco, Marcelo C.
Pest Management Science, 2000 , vol. 56, # 2 p. 168 - 174
