2-氯-6-甲基-4-三氟甲基烟腈合成路线 (共 2 条)
反应条件
trichlorophosphate 2 h; Reflux;
参考文献
CONSTELLATION PHARMACEUTICALS; ALBRECHT, Brian, K.; AUDIA, James, Edmund; COOK, Andrew; GAGNON, Alexandre; HARMANGE, Jean-christophe; NAVESCHUK, Christopher, G.
Patent: WO2013/75083 A1, 2013 ;
Location in patent: Paragraph 00402; 00404 ;
反应条件
1: methanol / 12 h / |Reflux 2: trichlorophosphate / 2 h / |Reflux View Scheme