6-甲基-2-吡啶甲酸甲酯合成路线

参考文献

ELI LILLY AND COMPANY
Patent: WO2007/18818 A1, 2007 ;
Location in patent: Page/Page column 11 ;
WO 2007/018818 A1

13602-11-46-甲基-2-吡啶甲酸甲酯+

924898-10-2

924898-11-3

参考文献

ELI LILLY AND COMPANY
Patent: WO2007/18818 A1, 2007 ;
Location in patent: Page/Page column 9 ;
WO 2007/018818 A1

4926-28-72-溴-4-甲基吡啶+

13602-11-46-甲基-2-吡啶甲酸甲酯

446880-80-42-(2-溴-4-吡啶)-1-(6-甲基-2-吡啶)乙酮

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/13138 A2, 2004 ;
Location in patent: Page 26 ;
WO 2004/013138 A2

491-35-04-甲基喹啉+

13602-11-46-甲基-2-吡啶甲酸甲酯

476472-02-31-(6-甲基吡啶)-2-喹啉-4-乙酮

参考文献

Sawyer, J. Scott; Beight, Douglas W.; Britt, Karen S.; Anderson, Bryan D.; Campbell, Robert M.; Goodson Jr., Theodore; Herron, David K.; Li, Hong-Yu; McMillen, William T.; Mort, Nicholas; Parsons, Stephen; Smith, Edward C. R.; Wagner, Jill R.; Yan, Lei; Zhang, Faming; Yingling, Jonathan M.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 13 p. 3581 - 3584

13602-11-46-甲基-2-吡啶甲酸甲酯

476472-56-72-(4-氟苯基)-1-(6-甲基-2-吡啶基)乙酮

参考文献

Sawyer, J. Scott; Anderson, Bryan D.; Beight, Douglas W.; Campbell, Robert M.; Jones, Michael L.; Herron, David K.; Lampe, John W.; McCowan, Jefferson R.; McMillen, William T.; Mort, Nicholas; Parsons, Stephen; Smith, Edward C. R.; Vieth, Michal; Weir, Leonard C.; Yan, Lei; Zhang, Faming; Yingling, Jonathan M.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 19 p. 3953 - 3956

13602-11-46-甲基-2-吡啶甲酸甲酯

41337-85-36-(羟基甲基)-2-吡啶甲酰肼

参考文献

Mathes et al.
Chemische Berichte, 1953 , vol. 86, p. 584,587

13602-11-46-甲基-2-吡啶甲酸甲酯

63668-37-16-甲基-2-吡啶羧酰胺

参考文献

Meyer
Recueil des Travaux Chimiques des Pays-Bas, 1925 , vol. 44, p. 328