反应条件
1.1: sodium carbonate / isopropanol acetate; water / 0.08 h / 20 °C / Inert atmosphere
1.2: 2 h / 20 °C / Inert atmosphere
2.1: potassium carbonate / N,N-dimethyl-formamide / 2.08 h / Inert atmosphere
3.1: lithium hydroxide hydrate / tetrahydrofuran; water / 4.25 h / 15 - 20 °C / Inert atmosphere
3.2: 2 h / pH 2.5 - 3.5 / Inert atmosphere
View Scheme
参考文献
Molinaro, Carmela; Bulger, Paul G.; Lee, Ernest E.; Kosjek, Birgit; Lau, Stephen; Gauvreau, Danny; Howard, Melissa E.; Wallace, Debra J.; O'Shea, Paul D.
Journal of Organic Chemistry, 2012 , vol. 77, # 5 p. 2299 - 2309
