2-(2-噻吩基)-1H-咪唑合成路线 （共 5 条）
反应条件
[bis(acetoxy)iodo]benzene; potassium carbonate in dimethyl sulfoxide T=20°C; 24 h;
参考文献
Haneda, Satoshi; Okui, Ayaka; Ueba, Chigusa; Hayashi, Masahiko
Tetrahedron, 2007 , vol. 63, # 11 p. 2414 - 2417
反应条件
1: 84 percent / p-toluenesulfonic acid / ethane-1,2-diol; H2O / 8 h / Heating 2: 37 percent / 2percent Pd/C / diphenyl ether / 2 h / Heating View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 27, # 10 p. 1140 - 1144
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 27, # 10 p. 1414 - 1418
反应条件
hydrogenchloride in methanol 5 h; Heating;
参考文献
Voss, Matthew E.; Beer, Catherine M.; Mitchell, Scott A.; Blomgren, Peter A.; Zhichkin, Paul E.
Tetrahedron, 2008 , vol. 64, # 4 p. 645 - 651
反应条件
1: 2-methyl-propan-2-ol / 20 °C 2: K2CO3; I2 / 2-methyl-propan-2-ol / 3 h / 70 °C 3: 70 percent / (diacetoxyiodo)benzene; K2CO3 / dimethylsulfoxide / 24 h / 20 °C View Scheme
参考文献
Synlett, , # 2 p. 227 - 230
反应条件
potassium hydroxide in ethylene glycol dimethyl ether T=8°C; 0.5 h;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 27, # 10 p. 1140 - 1144
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 27, # 10 p. 1414 - 1418
