7-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-3,4-二氢-2H-苯并[b][1,4]噁嗪合成路线 （共 4 条）
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate in 1,4-dioxane T=110°C; 16 h; Sealed tube;
参考文献
Trabanco, Andres A.; Tresadern, Gary; MacDonald, Gregor J.; Vega, Juan Antonio; De Lucas, Ana Isabel; Matesanz, Encarnacion; Garcia, Aranzazu; Linares, Maria Lourdes; Alonso De Diego, Sergio A.; Alonso, Jose Manuel; Oehlrich, Daniel; Ahnaou, Abdelah; Drinkenburg, Wilhelmus; MacKie, Claire; Andres, Jose Ignacio; Lavreysen, Hilde; Cid, Jose Maria
Journal of Medicinal Chemistry, 2012 , vol. 55, # 6 p. 2688 - 2701
反应条件
1: iron; ammonium chloride / ethanol; water / 0.5 h / 50 - 70 °C 2: caesium carbonate / acetonitrile / 20 °C 3: borane-THF / tetrahydrofuran / 1 h / |Inert atmosphere; |Reflux 4: 1,1'-bis-(diphenylphosphino)ferrocene; potassium acetate / 1,4-dioxane / 4 h / 110 °C / |Inert atmosphere View Scheme
参考文献
Lv, Yongcong; Li, Mengyuan; Liu, Ting; Tong, Linjiang; Peng, Ting; Wei, Lixin; Ding, Jian; Xie, Hua; Duan, Wenhu
ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 5 p. 592 - 597
反应条件
1: caesium carbonate / acetonitrile / 20 °C 2: borane-THF / tetrahydrofuran / 1 h / |Inert atmosphere; |Reflux 3: 1,1'-bis-(diphenylphosphino)ferrocene; potassium acetate / 1,4-dioxane / 4 h / 110 °C / |Inert atmosphere View Scheme
参考文献
Lv, Yongcong; Li, Mengyuan; Liu, Ting; Tong, Linjiang; Peng, Ting; Wei, Lixin; Ding, Jian; Xie, Hua; Duan, Wenhu
ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 5 p. 592 - 597
反应条件
1: borane-THF / tetrahydrofuran / 1 h / |Inert atmosphere; |Reflux 2: 1,1'-bis-(diphenylphosphino)ferrocene; potassium acetate / 1,4-dioxane / 4 h / 110 °C / |Inert atmosphere View Scheme
参考文献
Lv, Yongcong; Li, Mengyuan; Liu, Ting; Tong, Linjiang; Peng, Ting; Wei, Lixin; Ding, Jian; Xie, Hua; Duan, Wenhu
ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 5 p. 592 - 597
