1: 8 h / 0 °C / asymmetric hydrolysis with Lipase P, acetate buffer, pH 5 2: H2 / PtO2 / ethyl acetate / 2 h / 760 Torr / Ambient temperature 3: pyridine / 12 h / 0 °C 4: LiAlH4 / diethyl ether / 12 h / Heating View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: 95 percent / pyridine / 3 h / Ambient temperature<br />2: 97 percent / H₂ / Lindlar / ethyl acetate / 24 h / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: NaOEt / ethanol<br />2: (i) LiAlH₄, (ii) /BRN= 385737/<br />3: 515 &deg;C<br /> <br /> &nbsp;