5,7-二甲基-1-萘满酮合成路线 （共 25 条）
反应条件
hydrogenchloride; amalgamated zinc; acetic acid
参考文献
Krollpfeiffer; Schaefer
Chemische Berichte, 1923 , vol. 56, p. 630
参考文献
Heimgartner,H. et al.
Helvetica Chimica Acta, 1973 , vol. 56, p. 2924 - 2945
反应条件
1: With diisobutylaluminium hydride in hexane; dichloromethane
T=0°C; 2 h;
2: With water; NAF in hexane; dichloromethane
3 h; Product distribution / selectivity;
参考文献
Szewczyk, Jerzy Ryszard; Donaldson, Kelly H.
Patent: US2006/3991 A1, 2006 ;
Location in patent: Page/Page column 18; 20 ;
US 20060003991 A1
反应条件
trichlorophosphate
Vilsmeier-Haack Reaction;
参考文献
Hesse, Stephanie; Kirsch, Gilbert
Tetrahedron Letters, 2002 , vol. 43, # 7 p. 1213 - 1215
反应条件
1: With ammonium acetate; sodium cyanoborohydride in isopropyl alcohol
16 h; Heating / reflux;
2: With sodium hydroxide in water; isopropyl alcohol
参考文献
ALLERGAN, INC.
Patent: WO2009/23758 A1, 2009 ;
Location in patent: Page/Page column 10 ;
WO 2009/023758 A1
