2-(4-氯苯基)-4,5-二氢-1H-咪唑合成路线 （共 20 条）
反应条件
tetraphosphorus decasulfide 0.0625 h; microwave irradiation;
参考文献
Moghadam, Majid; Mohammadpoor-Baltork, Iraj; Mirkhani, Valiollah; Tangestaninejad, Shahram; Abdollahi-Alibeik, Mohammad; Yousefi, Behrooz H.; Kargar, Hadi
Monatshefte fur Chemie, 2007 , vol. 138, # 6 p. 579 - 583
反应条件
N-bromosuccinmide in dichloromethane T=0 - 20°C;
参考文献
Bai, Guo-Yi; Xu, Kai; Chen, Guo-Feng; Yang, Yong-Hui; Li, Tian-Yu
Synthesis, 2011 , # 10 art. no. H30011SS, p. 1599 - 1603
参考文献
Shi, Zhen; Gu, Huan
Synthetic Communications, 1997 , vol. 27, # 15 p. 2701 - 2707
反应条件
1: 4-chloro-1-hydroxymethyl-benzene With iodine; potassium carbonate in tert-butyl alcohol Heating; 2: ethylenediamine in tert-butyl alcohol Heating; Further stages.;
参考文献
Ren, Yi-Ming; Cai, Chun
Organic Preparations and Procedures International, 2008 , vol. 40, # 1 p. 101 - 105
反应条件
N-bromosuccinmide in water T=65 - 70°C; 0.3 h; Ultrasound irradiation;
参考文献
Sant' Anna, Gabriela da S.; Machado, Pablo; Sauzem, Patricia D.; Rosa, Fernanda A.; Rubin, Maribel A.; Ferreira, Juliano; Bonacorso, Helio G.; Zanatta, Nilo; Martins, Marcos A.P.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 2 p. 546 - 549
反应条件
1,3-bis-(diphenylphosphino)propane; caesium carbonate; palladium dichloride in toluene 16 h; Inert atmosphereReflux;
参考文献
Geden, Joanna V.; Pancholi, Alpa K.; Shipman, Michael
Journal of Organic Chemistry, 2013 , vol. 78, # 8 p. 4158 - 4164
参考文献
Crane, Louis J.; Anastassiadou, Maria; Stigliani, Jean-Luc; Baziard-Mouysset, Genevieve; Payard, Marc
Tetrahedron, 2004 , vol. 60, # 25 p. 5325 - 5330
反应条件
in 1,4-dioxane T=100°C; 7 h;
参考文献
Nenajdenko, Valentine G.; Muzalevskiy, Vasiliy M.; Shastin, Aleksey V.; Balenkova, Elizabeth S.; Kondrashov, Evgeniy V.; Ushakov, Igor A.; Rulev, Alexander Yu.
Journal of Organic Chemistry, 2010 , vol. 75, # 16 p. 5679 - 5688
反应条件
1: 83 percent / Et3N; aq. (NH4)2S / pyridine / 50 °C 2: 85 percent / 72 h / 120 °C View Scheme
参考文献
Crane, Louis J.; Anastassiadou, Maria; Stigliani, Jean-Luc; Baziard-Mouysset, Genevieve; Payard, Marc
Tetrahedron, 2004 , vol. 60, # 25 p. 5325 - 5330
反应条件
1: water / 0.03 h / Ultrasound irradiation 2: N-bromosuccinmide / water / 0.3 h / 65 - 70 °C / Ultrasound irradiation View Scheme
参考文献
Sant' Anna, Gabriela da S.; Machado, Pablo; Sauzem, Patricia D.; Rosa, Fernanda A.; Rubin, Maribel A.; Ferreira, Juliano; Bonacorso, Helio G.; Zanatta, Nilo; Martins, Marcos A.P.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 2 p. 546 - 549
