1,1-双(甲硫基)-2-亚硝基乙烯合成路线 （共 38 条）
反应条件
in hexane; toluene T=0°C; 2.5 h;
参考文献
Rao, H. Surya Prakash; Sivakumar
Journal of Organic Chemistry, 2005 , vol. 70, # 11 p. 4524 - 4527
反应条件
in N,N-dimethyl-formamide T=0 - 20°C; Inert atmosphere;
参考文献
NOVARTIS AG
Patent: US2011/190334 A1, 2011 ;
Location in patent: Page/Page column 16 ;
US 20110190334 A1
反应条件
sodium methylate in methanol
参考文献
Toyama Chemical Co., Ltd.
Patent: US4643849 A1, 1987 ;
US 4643849 A
反应条件
methanol in water 2 h; Ambient temperature;
参考文献
Contreras, Jean-Marie; Rival, Yveline M.; Chayer, Said; Bourguignon, Jean-Jacques; Wermuth, Camille G.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 4 p. 730 - 741
反应条件
1: carbon disulfide; nitromethane With potassium hydroxide in ethanol T=20°C; 0.5 h; 2: methyl iodide in N,N-dimethyl-formamide T=20°C; 1 h;
参考文献
Tian, Zhongzhen; Li, Zhong; Huang, Qingchun; Xu, Xiaoyong; Yu, Tao; Wu, Yingli; Qian, Xuhong
Journal of Chemical Research, 2006 , # 10 p. 626 - 628
反应条件
acetic acid in ethanol T=80 - 90°C; 4 h; Heating / reflux;
参考文献
Li, Zhong; Qian, Xuhong; Shao, Xusheng; Xu, Xiaoyong; Tian, Zhongzhen; Huang, Qingchun
Patent: US2009/111847 A1, 2009 ;
Location in patent: Page/Page column 8-9 ;
反应条件
in acetic acid 1.5 h; Heating;
参考文献
Schaefer,H.; Gewald,K.
Zeitschrift fuer Chemie (Stuttgart, Germany), 1976 , vol. 16, # 7 p. 272
反应条件
in methanol 8 h; Heating;
参考文献
He, Hongxia; Liu, Mengjia; Zheng, Zhibing; Liu, Ying; Xiao, Junhai; Su, Ruibin; Hu, Chun; Li, Jin; Li, Song
Molecules, 2006 , vol. 11, # 6 p. 393 - 402
反应条件
in methanol 18 h; Ambient temperatureother solvents, times, temperatures; MechanismProduct distribution;
参考文献
Sega, Alessandro; Toso, Roberto; Sunjic, Vitomir; Klasinc, Leo; Sabljic, Aleksandar; Srzic, Dunja
Gazzetta Chimica Italiana, 1981 , vol. 111, # 5/6 p. 217 - 222
反应条件
in methanol; methanolic methylamine; acetonitrile
参考文献
Allen and Hanburys Limited
Patent: US4128658 A1, 1978 ;
