1,1-双(甲硫基)-2-亚硝基乙烯合成路线 （共 38 条）
反应条件
ammonium acetate in ethanol 6 h; Heating;
参考文献
Mertens, Hubert; Troschuetz, Reinhard; Roth, Hermann J.
Liebigs Annalen der Chemie, 1986 , # 2 p. 380 - 383
参考文献
Shao, Xusheng; Zhang, Wenwen; Peng, Yanqing; Li, Zhong; Tian, Zhongzhen; Qian, Xuhong
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 24 p. 6513 - 6516
反应条件
1) methanol, ethanol, 2 h, 50 deg C, 2) ethanol, 3 h, 50 deg C; Yield given. Multistep reaction;
参考文献
Haywood, Phillip A.; Martin-Smith, Michael; Cholerton, Trevor J.; Evans, Michael B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 951 - 954
反应条件
in ethanol T=110°C; 1.5 h; Microwave irradiationInert atmosphere;
参考文献
Sangi, Diego P.; Correa, Arlene G.
Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 5 p. 795 - 799
反应条件
in ethanol 72 h; Heating;
参考文献
Manley; Quast
Journal of Medicinal Chemistry, 1992 , vol. 35, # 12 p. 2327 - 2340
反应条件
ammonia in methanol
T=50°C; 18 h;
参考文献
SUNESIS PHARMACEUTICALS, INC.
Patent: WO2006/65703 A1, 2006 ;
Location in patent: Page/Page column 105 ;
WO 2006/065703 A1
反应条件
in ethanol
1 h; Heating;
参考文献
Foks, Henryk; Pancechowska-Ksepko, Danuta; Janowiec, Mieczyslaw; Zwolska, Zofia; Augustynowicz-Kopec, Ewa
Phosphorus, Sulfur and Silicon and the Related Elements, 2005 , vol. 180, # 10 p. 2291 - 2297
反应条件
sodium hydroxide
1) EtOH, 40 deg C, 2 h, 2) heating, 2 h; Yield given. Multistep reaction;
参考文献
Haywood, Phillip A.; Martin-Smith, Michael; Cholerton, Trevor J.; Evans, Michael B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 951 - 954
反应条件
in ethanol
10 h; Heating;
参考文献
Ram
Archiv der Pharmazie, 1980 , vol. 313, # 5 p. 471 - 476
反应条件
hydrazine in ethanol
参考文献
Hamberger,H. et al.
Tetrahedron Letters, 1977 , p. 3619 - 3622
