4-(3-氧代-丙基)-苯甲腈合成路线 （共 6 条）
反应条件
diethyl-1,4-dihydro-2,6-dimethyl-3,5-pyridine dicarboxylate; (Bn2NH2)(OCOCF3) in tetrahydrofuran T=20°C; 5 h;
参考文献
Yang, Jung Woon; Hechavarria Fonseca, Maria T.; List, Benjamin
Angewandte Chemie - International Edition, 2004 , vol. 43, # 48 p. 6660 - 6662
反应条件
N,N-dicyclohexylmethylamine; bis(dibenzylideneacetone)-palladium(0); cataCXium PIntB in N,N-dimethyl-formamide T=100°C; 1 h; Inert atmosphere;
参考文献
Colbon, Paul; Ruan, Jiwu; Purdie, Mark; Mulholland, Keith; Xiao, Jianliang
Organic Letters, 2011 , vol. 13, # 20 p. 5456 - 5459
反应条件
hydrogen; N-hexadecyl-N,N,N-trimethylammonium bromide in propan-1-ol; water T=50°C; 16 h; regioselective reaction;
参考文献
Nairoukh, Zackaria; Blum, Jochanan
Journal of Molecular Catalysis A: Chemical, 2012 , vol. 358, p. 129 - 133
反应条件
Dess-Martin periodane in dichloromethane T=20°C; Dess-Martin oxidation;
参考文献
UNIVERSITEIT ANTWERPEN
Patent: WO2007/45496 A1, 2007 ;
Location in patent: Page/Page column 68-70; 75 ;
WO 2007/045496 A1
反应条件
1,4-diaza-bicyclo[2.2.2]octane; N,N'-dimethyl-N,N'-propyleneurea; [iridium(III)(2-phenylpyridine)3]; N-isopropyl-benzylamine; acetic acid in water T=23°C; Irradiation;
参考文献
Pirnot, Michael T.; Rankic, Danica A.; Martin, David B. C.; MacMillan, David W. C.
Science, 2013 , vol. 340, # 6127 p. 1593 - 1596
反应条件
pyrrolidine in N,N-dimethyl-formamide
T=115°C; 6 h; Inert atmosphere;
参考文献
Colbon, Paul; Ruan, Jiwu; Purdie, Mark; Mulholland, Keith; Xiao, Jianliang
Organic Letters, 2011 , vol. 13, # 20 p. 5456 - 5459
