1: 78 percent / pyridine / CH2Cl2 / 0.75 h / -30 - -10 °C 2: 1) NaH / 1) DMF, 0 deg C, 30 min, 2a) 0 deg C, 20 min, b) to r.t. over 30 min 3: 86 percent / Bu3SnH, 2,2'-azobis(2-methylpropionitrile) / toluene / 3 h / Heating 4: HBr, AcOH / CH2Cl2 / 3 h / Ambient temperature 5: 4 Angstroem molecular sieves / acetonitrile / 14 h / Ambient temperature 6: 95 percent / NH3 / tetrahydrofuran; methanol / 16 h / 100 °C View Scheme