N-芴甲氧羰基-L-苏氨酸烯丙基酯合成路线 （共 6 条）
反应条件
tetrabutylammomium bromide; water; sodium hydrogencarbonate in dichloromethane T=20°C; 20 h; Inert atmosphere;
参考文献
Wojnar, Joanna M.; Evans, Clive W.; Devries, Arthur L.; Brimble, Margaret A.
Australian Journal of Chemistry, 2011 , vol. 64, # 6 p. 723 - 731
反应条件
trifluoroacetic acid in dichloromethane 2 h;
参考文献
Marcinkowska; Borovickova; Slaninova; Grzonka
Polish Journal of Chemistry, 2007 , vol. 81, # 7 p. 1335 - 1344
反应条件
1: chloro-trimethyl-silane 2: hydrogenchloride / 1,4-dioxane; water / 0 - 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 52, # 22 p. 2808 - 2811
反应条件
1.1: water; sodium carbonate / 1,4-dioxane / Cooling with ice 1.2: 20 °C / Cooling with ice 1.3: pH 3.5 2.1: tetrabutylammomium bromide; water; sodium hydrogencarbonate / dichloromethane / 20 h / 20 °C / Inert atmosphere View Scheme
参考文献
Australian Journal of Chemistry, , vol. 64, # 6 p. 723 - 731
反应条件
1: 50 percent / silver perchlorate, silver carbonate, molecular sieves / toluene; CH2Cl2 / 14 h / -9 - 20 °C 2: 82 percent / 64 h / Ambient temperature 3: 95 percent / N-methylaniline, tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Vuljanic, Tatjana; Bergquist, Karl-Erik; Clausen, Henrik; Roy, Sarbani; Kihlberg, Jan
Tetrahedron, 1996 , vol. 52, # 23 p. 7983 - 8000
反应条件
1: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 1.5 h / -78 °C / Molecular sieve
2: acetic acid; zinc / 1.5 h / 0 - 20 °C
3: tetrakis(triphenylphosphine) palladium(0); N-methylaniline / tetrahydrofuran / 0.5 h / 20 °C
View Scheme
参考文献
Graham, Mark E.; Stone, Robin S.; Robinson, Phillip J.; Payne, Richard J.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 13 p. 2545 - 2551
