5-(叔丁基硫代)-2,2-二甲基-4-氧代戊酸乙酯合成路线 （共 4 条）
反应条件
N-ethyl-N,N-diisopropylamine in acetonitrile T=0 - 20°C;
参考文献
Synthetic Communications, , vol. 39, # 7 p. 1175 - 1185
反应条件
1: AcOH / toluene / 96 h / Ambient temperature 2: AlCl3 / CH2Cl2 / 3 h View Scheme
参考文献
Woods, Keith W.; Brooks, Clint D. W.; Maki, Robert G.; Rodriques, Karen E.; Bouska, Jennifer B.; Young, Patrick; Bell, Randy L.; Carter, George W.
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 13 p. 1547 - 1552
反应条件
sodium acetate; acetic acid in toluene T=20°C; Fischer Indole Synthesis; 120 h;
参考文献
AMIRA PHARMACEUTICALS, INC.
Patent: WO2008/67566 A1, 2008 ;
Location in patent: Page/Page column 99 ;
反应条件
acetic acid in toluene 96 h; Ambient temperature;
参考文献
Kolasa, Teodozyj; Bhatia, Pramila; Brooks, Clint D. W.; Hulkower, Keren I.; Bouska, Jennifer B.; Harris, Richard R.; Bell, Randy L.
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 3 p. 507 - 514
