tetrabutyl ammonium fluoride in tetrahydrofuran 0.5 h; Ambient temperature;

1: 1.) LDA / 1.) THF, from -78 deg C to -70 deg C, 1 h, 2.) THF, -78 deg C, 30 min 2: 75 percent / n-Bu4NF / tetrahydrofuran / 0.5 h / Ambient temperature View Scheme

1: 89 percent / imidazole / dimethylformamide / Ambient temperature 2: 1.) LDA / 1.) THF, from -78 deg C to -70 deg C, 1 h, 2.) THF, -78 deg C, 30 min 3: 75 percent / n-Bu4NF / tetrahydrofuran / 0.5 h / Ambient temperature View Scheme