1-(4-溴苯肼)-2-苯乙炔合成路线 （共 49 条）
反应条件
1,3-dimethyl-imidazolidin-2-one; potassium carbonate; triphenylphosphine; copper(l) chloride
T=120°C; 12 h;
参考文献
Ogawa, Daisuke; Li, Jing; Suetsugu, Masato; Jiao, Jiao; Iwasaki, Masayuki; Nishihara, Yasushi
Tetrahedron Letters, 2013 , vol. 54, # 6 p. 518 - 521
反应条件
copper diacetate; 4 A molecular sieve; sodium hydride in tetrahydrofuran
T=20°C; Title compound not separated from byproducts;
参考文献
Demir, Ayhan S.; Reis, Oemer; Emrullahoglu, Mustafa
Journal of Organic Chemistry, 2003 , vol. 68, # 26 p. 10130 - 10134
反应条件
1: 2,6-lutidine / CH2Cl2 / 0 - 20 °C
2: 2N NaOH / tetrahydrofuran / 1 h / 20 °C
3: 68 percent / toluene; tetrahydrofuran / -45 - 20 °C
View Scheme
参考文献
Katritzky, Alan R.; Abdel-Fattah, Ashraf A. A.; Wang, Mingyi
Journal of Organic Chemistry, 2002 , vol. 67, # 21 p. 7526 - 7529
反应条件
[{1-benzyl-3-(3,3-dimethyl-2-oxobutyl)imidazol-2-ylidene}2-PdBr2]; caesium carbonate; copper(I) bromide in water; N,N-dimethyl-formamide
T=100°C; Sonogashira coupling; 2 h;
参考文献
Ray, Lipika; Barman, Samir; Shaikh, Mobin M.; Ghosh, Prasenjit
Chemistry - A European Journal, 2008 , vol. 14, # 22 p. 6646 - 6655
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
Heating;
参考文献
Pena, Miguel A.; Perez Sestelo, Jose; Sarandeses, Luis A.
Synthesis, 2005 , # 3 art. no. Z14204SS, p. 485 - 492
反应条件
1: AlCl3
2: (i) PCl3, (ii) KOH
View Scheme
参考文献
Kotlyarevskii,I.L.; Popova,N.I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1967 , p. 205 - 207
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1967 , # 11 p. 208 - 210
反应条件
1: AlCl3
2: (i) PCl3, (ii) KOH
View Scheme
参考文献
Kotlyarevskii,I.L.; Popova,N.I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1967 , p. 205 - 207
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1967 , # 11 p. 208 - 210
反应条件
(i) PCl3, (ii) KOH; Multistep reaction;
参考文献
Kotlyarevskii,I.L.; Popova,N.I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1967 , p. 205 - 207
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1967 , # 11 p. 208 - 210
反应条件
potassium permanganate; tetraethylammonium bromide; sodium hydrogencarbonate in dichloromethane
T=20°C; 48 h;
参考文献
Ren, Wei; Xia, Yuanzhi; Ji, Shun-Jun; Zhang, Yong; Wan, Xiaobing; Zhao, Jing
Organic Letters, 2009 , vol. 11, # 8 p. 1841 - 1844
