(2-氧代环己基)-乙酸甲酯合成路线 （共 17 条）
反应条件
TASF-(Et) in tetrahydrofuran
T=-78°C; 2 h;
参考文献
Noyori, R.; Nishida, I.; Sakata, J.
Journal of the American Chemical Society, 1983 , vol. 105, # 6 p. 1598 - 1608
反应条件
Et3N*2HF in tetrahydrofuran
1 h; Ambient temperature;
参考文献
Kunkel, Elisabeth; Reichelt, Ingrid; Reissig, Hans-Ulrich
Liebigs Annalen der Chemie, 1984 , # 4 p. 802 - 819
反应条件
air; triethyl borane in hexane
T=20°C; 9 h;
参考文献
Miura, Katsukiyo; Fujisawa, Naoki; Saito, Hiroshi; Wang, Di; Hosomi, Akira
Organic Letters, 2001 , vol. 3, # 16 p. 2591 - 2594
反应条件
hydrogen; palladium on activated charcoal in tetrahydrofuran
T=57°C; 23 h;
参考文献
Brueckner, Christiane; Reissig, Hans-Ulrich
Chemische Berichte, 1987 , vol. 120, p. 617 - 626
反应条件
1: 75 percent / copper(II)-pentandionate / benzene / 90 °C
2: 83 percent / (C2H5)3NHF / tetrahydrofuran / 1 h / 25 °C
View Scheme
参考文献
Reissig, Hans-Ulrich; Hirsch, Elisabeth
Angewandte Chemie, 1980 , vol. 92, # 10 p. 839 - 840
反应条件
thionyl chloride
T=0°C; Reflux;
参考文献
Holloway, Chloe A.; Muratore, Michael E.; Storer, R. Lan; Dixon, Darren J.
Organic Letters, 2010 , vol. 12, # 21 p. 4720 - 4723
反应条件
Et3N*2HF in tetrahydrofuran
1 h; Ambient temperature; Yields of byproduct given;
参考文献
Kunkel, Elisabeth; Reichelt, Ingrid; Reissig, Hans-Ulrich
Liebigs Annalen der Chemie, 1984 , # 4 p. 802 - 819
反应条件
1: 68 percent / 2nd generation Grubbs catalyst / CH2Cl2 / 1 h / Heating
2: 85 percent / tert-dodecanethiol; AIBN / toluene / 19 h / Heating
View Scheme
参考文献
Yoshikai, Kazuya; Hayama, Tomoharu; Nishimura, Katsumi; Yamada, Ken-Ichi; Tomioka, Kiyoshi
Journal of Organic Chemistry, 2005 , vol. 70, # 2 p. 681 - 683
反应条件
aluminium trichloride in diethyl ether
参考文献
Hauptmann,S.; Hirschberg,K.
Journal fuer Praktische Chemie (Leipzig), 1966 , vol. 34, p. 272 - 282
反应条件
in tetrahydrofuran; methanol
2 h;
参考文献
Hassner, Alfred; Dillon, John
Journal of Organic Chemistry, 1986 , vol. 51, # 17 p. 3315 - 3319
