5-氧代-5-(2-吡啶基)戊酸合成路线 （共 4 条）
反应条件
1: 2-bromo-pyridine With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.5 h; 2: glutaric acid anhydride in tetrahydrofuran; hexane T=-78 - 20°C;
参考文献
Uyanik, Muhammet; Yasui, Takeshi; Ishihara, Kazuaki
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 14 p. 3848 - 3851
反应条件
oxygen; silica gel in dichloromethane 2 h;
参考文献
Houminer, Yoram
Journal of Organic Chemistry, 1985 , vol. 50, # 6 p. 786 - 789
反应条件
1: 1.) benzoyl chloride / 1.) CH2CL2, 0 deg C, 30 min, 2.) reflux, 5 h 2: 33 percent / silica gel, O2 / CH2Cl2 / 2 h View Scheme
参考文献
Houminer, Yoram
Journal of Organic Chemistry, 1985 , vol. 50, # 6 p. 786 - 789
反应条件
sulfuric acid T=85°C;
参考文献
Atobe, Masakazu; Maekawara, Naomi; Ishiguro, Noriko; Sogame, Shinya; Suenaga, Yoshihito; Kawanishi, Masashi; Suzuki, Hiroko; Jinno, Norimasa; Tanaka, Eiichi; Miyoshi, Shiro
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 7 p. 2106 - 2110
