2-羟基-6-甲氧基喹啉合成路线 （共 17 条）
反应条件
acetic anhydride T=75°C; 18 h; Yield given;
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 10 p. 2024 - 2028
反应条件
m-chloro-peroxy-benzoic acid; trifluoroacetic anhydride in chloroform; water; N,N-dimethyl-formamide
反应条件
phosphoric acid; phosphorus pentoxide T=110°C; 2 h;
参考文献
Inglis, Steven R.; Stojkoski, Cvetan; Branson, Kim M.; Cawthray, Jacquie F.; Fritz, Daniel; Wiadrowski, Emma; Pyke, Simon M.; Booker, Grant W.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 22 p. 5405 - 5417
反应条件
hydrogenchloride in ethanol 3 h; Heating;
参考文献
Shichiri; Funakoshi; Saeki; Hamana
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 2 p. 493 - 499
反应条件
hydrogenchloride in water 6 h; Reflux;
参考文献
Seyedi, Seyed Mohammad; Sadeghian, Hamid; Arghiani, Zahra
Heterocyclic Communications, 2008 , vol. 14, # 3 p. 183 - 186
反应条件
1: 37.7 percent / H2 / Pd/C / methanol 2: 34 percent / TsCl, Et3N / CHCl3; H2O / 12 h / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 28, # 2 p. 493 - 499
反应条件
1: 83 percent / pyridine; DMAP / CH2Cl2 / 0 - 20 °C 2: 69 percent / H3PO4; P2O5 / 2 h / 110 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 22 p. 5405 - 5417
反应条件
triethylamine; p-toluenesulfonyl chloride in chloroform-d1; water 12 h; Ambient temperature;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 28, # 2 p. 493 - 499
反应条件
toluene-4-sulfonic acid in toluene 14 h; Heating;
参考文献
Toda; Sakagami; Goan; Simakata; Saitoh; Horiguchi; Sano
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 12 p. 1854 - 1861
反应条件
6-methoxyquinoline N-oxide; triethylamine in chloroform; water 12 h; Ambient temperature;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 28, # 2 p. 493 - 499
