2-(4-氨基苯基)-5-氨基苯并恶唑合成路线 (共 5 条)
反应条件
hydrogen; palladium monocarbide in water
参考文献
The Dow Chemical Company
Patent: US5739344 A1, 1998 ;
反应条件
hydrogenchloride; sodium hypochlorite; 4-(N,N-dimethlyamino)pyridine; palladium in 1,4-dioxane; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; ethanol; water
反应条件
polyphosphoric acid (PPA) T=200°C; 0.5 h; Inert atmosphere;
参考文献
WO2010/111483 A1, ;
Page/Page column 83 ;
WO 2010/111483 A1
反应条件
palladium 10 on activated carbon; hydrogen in N,N-dimethyl-formamide T=20°C; 24 h;
参考文献
Li, Zhenyu; Zhan, Peng; Naesens, Lieve; Vanderlinden, Evelien; Liu, Ailin; Du, Guanhua; De Clercq, Erik; Liu, Xinyong
Chemical Biology and Drug Design, 2012 , vol. 79, # 6 p. 1018 - 1024
参考文献
Journal of Heterocyclic Chemistry, , vol. 6, p. 119 - 121