5-氯-2,4-二硝基苯甲酸合成路线 （共 6 条）
反应条件
sulfuric acid; potassium nitrate T=20 - 120°C;
参考文献
Wu, Hao; Xie, Xilei; Liu, Gang
Journal of Combinatorial Chemistry, 2010 , vol. 12, # 3 p. 346 - 355
反应条件
sulfuric acid; nitric acid T=140°C; 6 h;
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 13 p. 2518 - 2528
反应条件
chromium(VI) oxide; sulfuric acid
参考文献
Helvetica Chimica Acta, , vol. 35, p. 1330
反应条件
1: SOCl2 / 1 h / Heating 2: acetone / 0.25 h / 0 °C 3: 56 percent / 1 h / 50 °C View Scheme
参考文献
Palmer, Brian D.; Wilson, William R.; Cliffe, Stephen; Denny, William A.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3214 - 3222
反应条件
ethanol; nickel Hydrogenation;
参考文献
Goldstein; Stamm
Helvetica Chimica Acta, 1952 , vol. 35, p. 1470,1473
反应条件
1: SOCl2 / dimethylformamide / 4 h / Heating
2: conc. aq. NH4OH / 0.5 h / 0 °C
View Scheme
参考文献
Bristol-Myers Squibb Company
Patent: US6087368 A1, 2000 ;
US 6087368 A
