1-(4-氨基苯基)-2-吡咯烷酮合成路线 (共 5 条)
反应条件
copper(l) iodide; cesium fluoride; N-methyl-2-(methylamino)ethylamine in tetrahydrofuran T=25°C; 18 - 24 h; Inert atmosphere;
参考文献
Phillips, Dean P.; Zhu, Xue-Feng; Lau, Thomas L.; He, Xiaohui; Yang, Kunyong; Liu, Hong
Tetrahedron Letters, 2009 , vol. 50, # 52 p. 7293 - 7296
反应条件
water T=20°C; Inert atmosphere; chemoselective reaction;
参考文献
Dey, Raju; Mukherjee, Nirmalya; Ahammed, Sabir; Ranu, Brindaban C.
Chemical Communications, 2012 , vol. 48, # 64 p. 7982 - 7984
参考文献
Justus Liebigs Annalen der Chemie, , vol. 596, p. 1,209
反应条件
1: sulfuric acid; nitric acid 2: nickel-chromium oxide; methanol / 80 °C / 147102 Torr / Hydrogenation View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 596, p. 1,204
参考文献
BAYER HEALTHCARE AG
Patent: WO2004/101557 A1, 2004 ;
Location in patent: Page/Page column 31 ;