136918-14-4合成路线 （共 708 条）
反应条件
1: N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate / acetone / 24 h / 20 °C 2: potassium carbonate / N,N-dimethyl-formamide / 20 °C View Scheme
参考文献
Shan, Wen-Jun; Huang, Ling; Zhou, Qi; Meng, Fan-Chao; Li, Xing-Shu
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 12 p. 5885 - 5893
反应条件
1: 97 percent / CH2Cl2 / 3 h / 0 °C 2: 97 percent / triethylsilane; trifluoroboron etherate / CH2Cl2 / -15 - 20 °C View Scheme
参考文献
Wang, Eng-Chi; Chen, Hsien-Fan; Feng, Pei-Kuan; Lin, Yu-Li; Hsu, Ming-Kuan
Tetrahedron Letters, 2002 , vol. 43, # 50 p. 9163 - 9165
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C;
参考文献
Wang, You-Qing; Lu, Sheng-Mei; Zhou, Yong-Gui
Organic Letters, 2005 , vol. 7, # 15 p. 3235 - 3238
反应条件
SCl2; triethylamine 1.) CH2Cl2, 0 deg C, 2.) CH2Cl2, a) 0 deg C, 8 h, b) RT, 40 min; Yield given. Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 113, # 10 p. 3850 - 3866
反应条件
1: tetrabutylammomium bromide; potassium carbonate / dimethyl sulfoxide / 2.5 h / 75 °C 2: hydrogenchloride; water / dichloromethane / 1 h / 20 °C 3: sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 0.33 h / 20 °C View Scheme
参考文献
Kowalski, Piotr; Jaskowska, Jolanta
Archiv der Pharmazie, 2012 , vol. 345, # 1 p. 81 - 85
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran 14 h;
参考文献
Synthetic Communications, , vol. 23, # 17 p. 2443 - 2449
反应条件
1.1: nitric acid; sulfuric acid / 16 h / 5 - 20 °C 2.1: potassium hydroxide / methanol; ethanol / 3 h / 20 °C 2.2: 1 h / |Reflux View Scheme
参考文献
Bian, Xiaoli; Wang, Qian; Ke, Changhu; Zhao, Guilan; Li, Yiping
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 7 p. 2022 - 2026
反应条件
1: With [bis(acetoxy)iodo]benzene T=145°C; 3 h; Microwave irradiation; 2: With hydrazine hydrate in water; acetonitrile
参考文献
Kantak, Abhishek A.; Potavathri, Shathaverdhan; Barham, Rose A.; Romano, Kaitlyn M.; Deboef, Brenton
Journal of the American Chemical Society, 2011 , vol. 133, # 49 p. 19960 - 19965
反应条件
[bis(acetoxy)iodo]benzene
T=145°C; 3 h; Microwave irradiation;
参考文献
Kantak, Abhishek A.; Potavathri, Shathaverdhan; Barham, Rose A.; Romano, Kaitlyn M.; Deboef, Brenton
Journal of the American Chemical Society, 2011 , vol. 133, # 49 p. 19960 - 19965
反应条件
tri-tert-butyl phosphine; [bis(acetoxy)iodo]benzene; palladium diacetate
T=100°C; 33 h; Inert atmosphereGlovebox;
参考文献
Shrestha, Ruja; Mukherjee, Paramita; Tan, Yichen; Litman, Zachary C.; Hartwig, John F.
Journal of the American Chemical Society, 2013 , vol. 135, # 23 p. 8480 - 8483
