136918-14-4合成路线 （共 708 条）
反应条件
[bis(acetoxy)iodo]benzene
T=140°C; 4 h; chemoselective reaction;
参考文献
Shrestha, Ruja; Mukherjee, Paramita; Tan, Yichen; Litman, Zachary C.; Hartwig, John F.
Journal of the American Chemical Society, 2013 , vol. 135, # 23 p. 8480 - 8483
反应条件
[bis(acetoxy)iodo]benzene
T=140°C; 4 h; chemoselective reaction;
参考文献
Kim, Hyun Jin; Kim, Jiyu; Cho, Seung Hwan; Chang, Sukbok
Journal of the American Chemical Society, 2011 , vol. 133, # 41 p. 16382 - 16385
参考文献
Cernuskova l.; Benes; Csollei; Tumova; Svec
Pharmazie, 1994 , vol. 49, # 9 p. 646 - 649
反应条件
chlorine; triethylamine in tetrahydrofuran; tetrachloromethane; sodium hydroxide; chloroform; water
参考文献
The Goodyear Tire and Rubber Company
Patent: US3944552 A1, 1976 ;
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran
T=0 - 20°C; Mitsunobu reaction;
参考文献
Wiecek, Malgorzata; Kiec-Kononowicz, Katarzyna
Acta Poloniae Pharmaceutica - Drug Research, 2009 , vol. 66, # 3 p. 249 - 257
反应条件
[(PPh3)3Pd] in N,N-dimethyl-formamide
T=60°C; 5 h;
参考文献
Inoue, Yoshio; Taguchi, Masaaki; Toyofuku, Masanori; Hashimoto, Harukichi
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 10 p. 3021 - 3022
反应条件
[Pd(η3-1-Ph-allyl)(μ-Cl)]2; 1,3-bis-(diphenylphosphino)propane; sodium carbonate in toluene
T=140°C; 20 h; Inert atmosphere; regioselective reaction;
参考文献
Banerjee, Debasis; Junge, Kathrin; Beller, Matthias
Angewandte Chemie - International Edition, 2014 , vol. 53, # 6 p. 1630 - 1635
Angew. Chem., 2014 , vol. 126, # 6 p. 1656 - 1661,6
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20°C;
参考文献
Onajole, Oluseye K.; Govender, Patrick; Helden, Paul D. van; Kruger, Hendrik G.; Maguire, Glenn E.M.; Wiid, Ian; Govender, Thavendran
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 5 p. 2075 - 2079
反应条件
tetra-(n-butyl)ammonium iodide; caesium carbonate in water; N,N-dimethyl-formamide
参考文献
Ino, Yoji; Amishiro, Nobuyoshi; Miyata, Mayumi; Agatsuma, Tsutomu; Muramatsu, Kozue; Takahashi, Takeshi
Patent: US2003/216362 A1, 2003 ;
反应条件
caesium carbonate in N,N-dimethyl-formamide
T=20°C; 0.5 h;
参考文献
Cui, Jingrong Jean; Araldi, Gian-Luca; Reiner, John E.; Reddy, Komandla Malla; Kemp, Scott J.; Ho, Jonathan Z.; Siev, Daniel V.; Mamedova, Lala; Gibson, Tony S.; Gaudette, John A.; Minami, Nathaniel K.; Anderson, Susanne M.; Bradbury, Annette E.; Nolan, Thomas G.; Semple
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 20 p. 2925 - 2930
