136918-14-4合成路线 （共 708 条）
反应条件
1: phthalimide With potassium hydroxide; Amberlite IRA-400 chloride form
2: 1,5-dibromo-pentane in tetrahydrofuran
Heating;
参考文献
Dalal; Pawar; Mahulikar
Organic Preparations and Procedures International, 2007 , vol. 39, # 1 p. 81 - 85
反应条件
potassium carbonate in acetone
16 h; Reflux;
参考文献
Prabhakar; Kumar, N. Vasanth; Reddy, M. Ravikanth; Sarma; Reddy, G. Om
Organic Process Research and Development, 1999 , vol. 3, # 3 p. 155 - 160
反应条件
1: phthalimide With potassium hydroxide in ethanol
2: 1-chloro-2-(2-chloroethoxy)ethane in ethanol
参考文献
Wu, Huilu; Pan, Guolong; Bai, Yuchen; Wang, Hua; Kong, Jin; Shi, Furong; Zhang, Yanhui; Wang, Xiaoli
Journal of Coordination Chemistry, 2013 , vol. 66, # 15 p. 2634 - 2646
反应条件
DCAD; triphenylphosphine in dichloromethane
T=20°C; Mitsunobu reaction; 1.5 h;
参考文献
Lipshutz, Bruce H.; Chung, David W.; Rich, Brian; Corral, Ricardo
Organic Letters, 2006 , vol. 8, # 22 p. 5069 - 5072
反应条件
1.1: nitric acid; sulfuric acid / 16 h / 5 - 20 °C
2.1: potassium hydroxide / methanol; ethanol / 3 h / 20 °C
2.2: 1 h / |Reflux
3.1: palladium on activated charcoal; ammonium formate / tetrahydrofuran / 12 h / 20 °C
View Scheme
参考文献
Bian, Xiaoli; Wang, Qian; Ke, Changhu; Zhao, Guilan; Li, Yiping
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 7 p. 2022 - 2026
参考文献
Oda; Teramura
Bl.Inst.chem.Res.Kyoto Univ., 1954 , vol. 32, p. 159,163
反应条件
aluminum oxide; potassium fluoride in N,N-dimethyl-formamide
T=20°C; Michael addition reaction; 24 h;
参考文献
Yang, Lei; Xu, Li-Wen; Xia, Chun-Gu
Tetrahedron Letters, 2005 , vol. 46, # 19 p. 3279 - 3282
反应条件
caesium carbonate; sodium iodide in N,N-dimethyl-formamide
T=55°C; 0.583333 h; Microwave irradiationMolecular sieve;
参考文献
Escudero, Mercedes Isasmendi; Kremenchuzky, Lautaro D.; Perillo, Isabel A.; Cerecetto, Hugo; Blanco, Maria M.
Synthesis, 2011 , # 4 art. no. M06310SS, p. 571 - 576
反应条件
1: ethanol; hydrazine hydrate / anschliessenden Erwaermen
2: acetic acid
View Scheme
参考文献
Drew; Hatt
Journal of the Chemical Society, 1937 , p. 16,25
反应条件
triethylamine in tetrahydrofuran
9 h; Heating;
参考文献
Movassagh, Barahman; Zakinezhad, Yousef
Journal of Chemical Research, 2006 , # 6 p. 369 - 370
