(2,4-二氯苯基)环氧乙烷合成路线 （共 7 条）
反应条件
methyl lithium LiBr complex in tetrahydrofuran; hexanes T=0 - 20°C; 2 h;
参考文献
SCHERING CORPORATION
Patent: WO2006/60461 A1, 2006 ;
Location in patent: Page/Page column 190 ;
WO 2006/060461 A1
反应条件
potassium hydroxide in acetonitrile T=60°C; epoxidation; 3 h;
参考文献
Cruz-Almanza, Raymundo; Hernandez, Teresa; Perez, Francisco; Lemini, Cristina
Organic Preparations and Procedures International, 1992 , vol. 24, # 3 p. 342 - 345
反应条件
sodium methylate 1.) CH3CN; Multistep reaction;
参考文献
Ono; Yamafuji; Chaki; Morita; Todo; Maekawa; Kitamura; Tai; Narita
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 9 p. 1488 - 1491
反应条件
ammonia; iodine in water; acetonitrile T=70°C;
参考文献
Jadhav, Ravindra R.; Akamanchi, Krishnacharya G.
Chemistry Letters, 2013 , vol. 42, # 2 p. 162 - 164
反应条件
pyridine in ethanol Ring cleavage; 12 h; Heating;
参考文献
Cruz-Almanza, Raymundo; Hernandez, Teresa; Perez, Francisco; Lemini, Cristina
Organic Preparations and Procedures International, 1992 , vol. 24, # 3 p. 342 - 345
反应条件
1.1: 63 percent / pyridine / ethanol / 12 h / Heating 2.1: NaH; HMPA / tetrahydrofuran / 0.5 h / 20 °C 2.2: 73 percent / tetrahydrofuran / 16 h / 45 °C View Scheme
参考文献
Cruz-Almanza, Raymundo; Hernandez, Teresa; Perez, Francisco; Lemini, Cristina
Organic Preparations and Procedures International, 1992 , vol. 24, # 3 p. 342 - 345
反应条件
diphosphorous tetraiodide; tetraethylammonium bromide; water in dichloromethane T=20°C; 6 h; regioselective reaction;
参考文献
Telvekar, Vikas N.; Rane, Rajesh A.
Synthetic Communications, 2010 , vol. 40, # 14 p. 2108 - 2112
