(±)-2-甲基-1-丁醇合成路线 （共 128 条）
反应条件
Rhizomucor miehei lipase in n-heptane T=40°C; 24 h; Enzymatic reaction;
参考文献
Divakar, Soundar
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 9 p. 1919 - 1922
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran 48 h;
参考文献
Anteunis, M.J.O.; Spiessens, L.; Witte, M. De; Callens, R.; Reyniers, Fr.
Bulletin des Societes Chimiques Belges, 1987 , vol. 96, # 6 p. 459 - 466
反应条件
rhenic(VII) acid in water T=170°C; 4 h; Inert atmosphere;
参考文献
Shiramizu, Mika; Toste, F. Dean
Angewandte Chemie - International Edition, 2013 , vol. 52, # 49 p. 12905 - 12909
Angew. Chem., 2013 , vol. 125, # 49 p. 13143 - 13147,5
反应条件
sodium lauryl sulfate; sodium hydroxide; palladium dichloride; (4-dimethylaminophenyl)-diphenylphosphine in water T=44.84°C; P=760 Torr; Inert atmosphere; Kinetics;
参考文献
Norman, Carnley; Wilhite, Benjamin A.; Pham, Due; Lim, Phooi K.; Brown, Philip A.
Organic Process Research and Development, 1998 , vol. 2, # 6 p. 366 - 378
参考文献
Lieben; Zeisel
Monatshefte fuer Chemie, 1886 , vol. 7, p. 68
参考文献
Streitwieser et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 1110
反应条件
(i) SOCl2, Py, (ii) Na, cyclohexane; Multistep reaction;
参考文献
Skell,P.S. et al.
Journal of the American Chemical Society, 1976 , vol. 98, p. 1195 - 1204
反应条件
1.1: pyridine / 3 h / 0 - 5 °C
2.1: magnesium / tetrahydrofuran
2.2: 49 h / -78 - 20 °C / Inert atmosphere
3.1: Grubb's 2nd generation catalyst / dichloromethane / Inert atmosphere; Reflux
4.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 1 h / 20 °C
View Scheme
参考文献
Mori, Kenji
Bioscience, Biotechnology and Biochemistry, 2010 , vol. 74, # 3 p. 595 - 600
参考文献
Streitwieser et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 1110
参考文献
Tanner,D.D. et al.
Journal of the American Chemical Society, 1971 , vol. 93, p. 4802 - 4808
