(±)-2-甲基-1-丁醇合成路线 （共 128 条）
反应条件
zinc(II) chloride
T=165 - 170°C;
参考文献
Abbott Labor.
Patent: US2073995 , 1934 ;
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Abbott Labor.
Patent: US2106760 , 1934 ;
反应条件
1: PBr3
2: Mg / diethyl ether
View Scheme
参考文献
Fraenkel,G.; Dix,D.T.
Journal of the American Chemical Society, 1966 , vol. 88, p. 979 - 985
反应条件
triethylamine in dichloromethane
T=23°C; 30 h;
参考文献
Feldman, Paul L.; James, Michael K.; Brackeen, Marcus F.; Bilotta, Joanne M.; Schuster, Suzanne V.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 7 p. 2202 - 2208
反应条件
tributylphosphine
T=49.85°C; Michael addition; P=2250180 Torr; 22 h;
参考文献
Jenner
Tetrahedron, 2002 , vol. 58, # 21 p. 4311 - 4317
反应条件
Rhizomucor miehei lipase in n-heptane
T=40°C; 24 h; Enzymatic reaction;
参考文献
Divakar, Soundar
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 9 p. 1919 - 1922
参考文献
CIBA-Geigy
Patent: BE840884 , 1976 ;
Chem.Abstr., 1977 , vol. 87, # 34408
反应条件
toluene-4-sulfonic acid
Heating;
参考文献
CIBA-Geigy
Patent: BE840884 , 1976 ;
Chem.Abstr., 1977 , vol. 87, # 34408
反应条件
sodium hydride; [BMMIM][PF6]
T=25°C; Williamson synthesis; 2 h;
参考文献
Xu, Zhen Yuan; Xu, Dan Qian; Liu, Bao You
Organic Preparations and Procedures International, 2004 , vol. 36, # 2 p. 156 - 161
反应条件
PPA
T=180 - 190°C; 4 h;
参考文献
Van Dyke Tiers, George
Acta Chemica Scandinavica, 1998 , vol. 52, # 10 p. 1223 - 1233
参考文献
Young; Roberts; Wax
Journal of the American Chemical Society, 1945 , vol. 67, p. 842
