toluene; phosphorus trichoride

T=220°C;

1: 3-hydroxy-[2]naphthoic acid-(5-chloro-2-methoxy-anilide) in water T=20 - 80°C; Alkaline conditions; 2: C14H12N3O2(1+)*Na(1+) With sodium acetate; acetic acid in water T=20 - 35°C; pH=4.8 - 5.0; Micro-reactor; Product distribution / selectivity;

1: 3-hydroxy-[2]naphthoic acid-(5-chloro-2-methoxy-anilide) in water T=20 - 80°C; Alkaline conditions; 2: C14H12N3O2(1+)*Na(1+) With sodium acetate; acetic acid in water T=20 - 35°C; pH=4.8 - 5.0; Micro-reactor; Product distribution / selectivity;