1: in tetrahydrofuran; diethyl ether T=0 - 5°C; 2 h; 2: With hydrogenchloride in tetrahydrofuran; diethyl ether T=20°C;

potassium hydride 1.) THF, 1 h, 2.) 16 h; Yield given. Multistep reaction;

1.1: LDA / tetrahydrofuran / 0.5 h / 0 - 5 °C 1.2: 88 percent / tetrahydrofuran / 2 h / 0 - 5 °C 2.1: diethyl ether; tetrahydrofuran / 2 h / 0 - 5 °C 2.2: 91 percent / aq. HCl / diethyl ether; tetrahydrofuran / 20 °C View Scheme

1: LiNEt2 2: (i), (ii) aq. AcOH View Scheme

(i) Li, liq. NH3, Et2O, tBuOH, (ii) /BRN= 969135/; Multistep reaction;

(i), (ii) aq. AcOH; Multistep reaction;