1: 90 percent / H2 / Raney Ni / ethyl acetate; methanol / 4 h / Ambient temperature 2: LDA / 0.08 h / -78 °C 3: 1) TFAA, DMSO 2) K-selectride / 1) 16h, 0 deg C; 2) Et2O, 0.5h 4: 1) imidazole 2) Jones reagent / 1) DMF View Scheme