1: 1N NaOH / H2O; CH2Cl2 / 1 h / Ambient temperature; pH 8.0 2: Bu3P, water / methanol / 1 h / Ambient temperature 3: 1N NaOH / methanol; H2O / 1.5 h / Ambient temperature View Scheme

1: SOCl2 / 4 h / Heating 2: 1N NaOH / H2O; CH2Cl2 / 1 h / Ambient temperature; pH 8.0 3: Bu3P, water / methanol / 1 h / Ambient temperature 4: 1N NaOH / methanol; H2O / 1.5 h / Ambient temperature View Scheme

1: Bu3P, water / methanol / 1 h / Ambient temperature 2: 1N NaOH / methanol; H2O / 1.5 h / Ambient temperature View Scheme

sodium hydroxide in methanol; water 1.5 h; Ambient temperature;