hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide T=90 - 100°C; 0.5 h;

1: 1.) methylmagnesium iodide / 1.) benzene, diethyl ether, RT, 0.5 h, 2.) benzene, diethyl ether, reflux, 65 h 2: KOH / ethanol / 1 h / Heating 3: 65 percent / hydroxylamine hydrochloride, potassium carbonate / H2O; dimethylformamide / 3 h / 80 °C View Scheme

1: KOH / ethanol / 1 h / Heating 2: 65 percent / hydroxylamine hydrochloride, potassium carbonate / H2O; dimethylformamide / 3 h / 80 °C View Scheme