bis(1,2-diphenylphosphino)benzene; copper (II) acetate monohydrate; lithium tert-butylate in tetrahydrofuran T=20°C; Chan-Lam type coupling; Inert atmosphere;

bis(1,2-diphenylphosphino)benzene; copper (II) acetate monohydrate; lithium tert-butylate in tetrahydrofuran T=20°C; Chan-Lam type coupling; 4 h; Inert atmosphere;

biphenyl-2-yl-di-tert-butyl-phosphane in 1,4-dioxane T=20°C; 4 h;

[(Mes)Cu]n; biphenyl-2-yl-di-tert-butyl-phosphane; lithium tert-butylate in 1,4-dioxane T=20°C; 4 h;

1.1: toluene-4-sulfonic acid / 20 °C 2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C 2.2: -78 - 20 °C 3.1: toluene-4-sulfonic acid / methanol / 16 h / 20 °C 4.1: tetrahydrofuran; diethyl ether / 4 h / -78 - 20 °C 5.1: biphenyl-2-yl-di-tert-butyl-phosphane; lithium tert-butylate; [(Mes)Cu]n / 1,4-dioxane / 4 h / 20 °C View Scheme

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C 1.2: -78 - 20 °C 2.1: toluene-4-sulfonic acid / methanol / 16 h / 20 °C 3.1: tetrahydrofuran; diethyl ether / 4 h / -78 - 20 °C 4.1: biphenyl-2-yl-di-tert-butyl-phosphane; lithium tert-butylate; [(Mes)Cu]n / 1,4-dioxane / 4 h / 20 °C View Scheme

1: tetrahydrofuran; diethyl ether / 4 h / -78 - 20 °C 2: biphenyl-2-yl-di-tert-butyl-phosphane; lithium tert-butylate; [(Mes)Cu]n / 1,4-dioxane / 4 h / 20 °C View Scheme

1: 2-Bromo-1,3,5-trimethyl-benzene With tert.-butyl lithium in tetrahydrofuran; pentane T=-78 - -20°C; 1 h; Inert atmosphere; 2: With copper(l) chloride in tetrahydrofuran; pentane T=-78°C; 1 h; Inert atmosphere; 3: Bn2N-OBz in tetrahydrofuran; pentane T=20°C; 4 h; Inert atmosphere;

bis(1,2-diphenylphosphino)benzene; copper (II) acetate monohydrate; lithium tert-butylate in tetrahydrofuran T=20°C; Chan-Lam type coupling; Inert atmosphere;

1: Inert atmosphere 2: bis(1,2-diphenylphosphino)benzene; copper (II) acetate monohydrate; lithium tert-butylate / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere View Scheme