sulfuric acid; iodine; iodic acid; acetic acid in water T=80°C; 3 h;

iodine in chloroform; acetone

1: 98 percent / hydrochloric acid, acetic acid / H2O / 0.33 h / Heating 2: 84 percent / acetic acid, sulfuric acid, iodic acid, iodine / H2O / 3 h / 80 °C View Scheme

1: 1.) tert-butyllithium / 1.) diethyl ether, pentane, -78 deg C, 1 h, 2.) diethyl ether, 30 min 2: 98 percent / hydrochloric acid, acetic acid / H2O / 0.33 h / Heating 3: 84 percent / acetic acid, sulfuric acid, iodic acid, iodine / H2O / 3 h / 80 °C View Scheme

1: 1.) hydrochloric acid, sodium nitrite, 2.) potassium iodide / 1.) water, 0 deg C, 45 min, 2.) water, overnight 2: 1.) tert-butyllithium / 1.) diethyl ether, pentane, -78 deg C, 1 h, 2.) diethyl ether, 30 min 3: 98 percent / hydrochloric acid, acetic acid / H2O / 0.33 h / Heating 4: 84 percent / acetic acid, sulfuric acid, iodic acid, iodine / H2O / 3 h / 80 °C View Scheme

in N,N-dimethyl-formamide T=145°C; 4 h;