1-苯甲酰基-1,2-二氢-2-喹啉甲腈合成路线 (共 30 条)
反应条件
sodium hydroxide; bromine
1.) RT, 2 h, 2.) RT, 20 h; Yield given. Multistep reaction;
参考文献
Sugiura, Michiharu; Sakurai, Yoshie; Hamada, Yoshiki
Heterocycles, 1992 , vol. 34, # 3 p. 561 - 568
反应条件
dihydrogen peroxide; lithium hydroxide hydrate in water; acetone
T=0°C; 0.25 h;
参考文献
Jean-Gerard, Ludivine; MacE, Frederic; Ngo, Anh Ngoc; Pauvert, Mickael; Dentel, Helene; Evain, Michel; Collet, Sylvain; Guingant, Andre
European Journal of Organic Chemistry, 2012 , # 22 p. 4240 - 4248
反应条件
diethyl ether
und Dioxan bei -10grad mit aether.Phenyllithium-Loesung und anschliessend mit aether.Benzaldehyd-Loesung;
参考文献
Walters et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 1177,1181
参考文献
Walters et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 1177,1181
反应条件
formic acid
T=20°C; Reissert reaction; 20 h;
参考文献
Friedrich, Klaus; Zamkanei, Mohebullah; Zimmer, Ralph
Advanced Synthesis and Catalysis, 2000 , vol. 342, # 4 p. 404 - 408
参考文献
Reissert
Chemische Berichte, 1905 , vol. 38, p. 1610
反应条件
1: aqueous HBr; acetic acid
2: aqueous NaOH
View Scheme
参考文献
Davis
Journal of Organic Chemistry, 1959 , vol. 24, p. 1691,1693, 1694
反应条件
1,4-dioxane; diethyl ether; phenyllithium
Erhitzen des Reaktionsprodukts in wss. KOH;
参考文献
Boekelheide; Godfrey
Journal of the American Chemical Society, 1953 , vol. 75, p. 3679,3682
反应条件
sodium hydroxide; oxygen; benzyltriethylammonium hydroxide in water; benzene
Ambient temperature;
参考文献
Rozwadowska, Maria; Brozda, Danuta
Canadian Journal of Chemistry, 1980 , vol. 58, p. 1239 - 1242
反应条件
sulfuric acid; nitric acid; acetic anhydride
12 h;
参考文献
Sugiura; Hatano; Hirao; Mogi; Kurono; Tashiro; Usami; Hamada
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 9 p. 2262 - 2266