n-叔丁氧基羰基-3-(4-联苯)-2-氨基丙酸-(S)-甲酯合成路线 （共 9 条）
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in toluene T=85 - 90°C; 2 h; other arylboronic acids; Product distribution;
参考文献
Shieh, Wen-Chung; Carlson, John A.
Journal of Organic Chemistry, 1992 , vol. 57, # 1 p. 379 - 381
反应条件
nitrogen; potassium carbonate; tetrakis (triphenylphosphine) palladium (0) in toluene
参考文献
Ciba-Geigy Corporation
Patent: US5294632 A1, 1994 ;
Title/Abstract Full Text Show Details
Ciba-Geigy Corporation
Patent: US5155100 A1, 1992 ;
反应条件
tris-(dibenzylideneacetone)dipalladium(0); triphenyl-arsane in N,N-dimethyl-formamide T=60°C; 2 h;
参考文献
Morera, Enrico; Ortar, Giorgio
Synlett, 1997 , # 12 p. 1403 - 1405
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in tetrahydrofuran; toluene Suzuki-Miyaura coupling;
参考文献
Kotha; Lahiri
Bioorganic and medicinal chemistry letters, 2001 , vol. 11, # 21 p. 2887 - 2890
反应条件
1: Et3N / CHCl3 2: 91 percent / Pd(PPh3)4; aq. Na2CO3 / tetrahydrofuran; toluene View Scheme
参考文献
Kotha; Lahiri
Bioorganic and medicinal chemistry letters, 2001 , vol. 11, # 21 p. 2887 - 2890
反应条件
sodium hydroxide in tetrahydrofuran; methanol Ambient temperature;
参考文献
Ksander, Gary M.; Ghai, Raj D.; deJesus, Reynalda; Diefenbacher, Clive G.; Yuan, Andrew; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 10 p. 1689 - 1700
反应条件
sodium hydroxide in tetrahydrofuran; methanol Ambient temperature;
参考文献
Ksander, Gary M.; Ghai, Raj D.; deJesus, Reynalda; Diefenbacher, Clive G.; Yuan, Andrew; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 10 p. 1689 - 1700
反应条件
sodium hydroxide in tetrahydrofuran; methanol Ambient temperature;
参考文献
Ksander, Gary M.; Ghai, Raj D.; deJesus, Reynalda; Diefenbacher, Clive G.; Yuan, Andrew; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 10 p. 1689 - 1700
反应条件
hydrogenchloride in ethyl acetate
3 h; Ambient temperature;
参考文献
Shieh, Wen-Chung; Carlson, John A.
Journal of Organic Chemistry, 1992 , vol. 57, # 1 p. 379 - 381
