2-(4-氯-3-甲氧基苯基)乙酸合成路线 （共 8 条）
参考文献
Shionogi Co., Ltd.
Patent: EP1887000 A1, 2008 ;
Location in patent: Page/Page column 106-107 ;
反应条件
1: HCHO, MeOH, aq. KOH 2: SOCl2, Py / diethyl ether / Heating 4: aq. KOH View Scheme
参考文献
Munavalli,S. et al.
Bulletin de la Societe Chimique de France, 1966 , p. 3311 - 3318
反应条件
1: SOCl2, Py / diethyl ether / Heating 3: aq. KOH View Scheme
参考文献
Munavalli,S. et al.
Bulletin de la Societe Chimique de France, 1966 , p. 3311 - 3318
反应条件
1: SnCl2, aq. HCl 2: (i) aq. NaNO2, aq. HCl, (ii) /BRN= 1697325/, CuSO4, Na2SO3, NaOAc 3: HCHO, MeOH, aq. KOH 4: SOCl2, Py / diethyl ether / Heating 6: aq. KOH View Scheme
参考文献
Munavalli,S. et al.
Bulletin de la Societe Chimique de France, 1966 , p. 3311 - 3318
反应条件
1: (i) aq. NaNO2, aq. HCl, (ii) /BRN= 1697325/, CuSO4, Na2SO3, NaOAc 2: HCHO, MeOH, aq. KOH 3: SOCl2, Py / diethyl ether / Heating 5: aq. KOH View Scheme
参考文献
Munavalli,S. et al.
Bulletin de la Societe Chimique de France, 1966 , p. 3311 - 3318
反应条件
1: (i) NaNO2, aq. HCl, (ii) CuCl 2: SnCl2, aq. HCl 3: (i) aq. NaNO2, aq. HCl, (ii) /BRN= 1697325/, CuSO4, Na2SO3, NaOAc 4: HCHO, MeOH, aq. KOH 5: SOCl2, Py / diethyl ether / Heating 7: aq. KOH View Scheme
参考文献
Munavalli,S. et al.
Bulletin de la Societe Chimique de France, 1966 , p. 3311 - 3318
反应条件
2: aq. KOH View Scheme
参考文献
Munavalli,S. et al.
Bulletin de la Societe Chimique de France, 1966 , p. 3311 - 3318
反应条件
water; hydrogen bromide; acetic acid in water
24 h; Heating / reflux;
参考文献
ASTRAZENECA AB
Patent: US2008/293775 A1, 2008 ;
Location in patent: Page/Page column 22 ;
US 20080293775 A1
