N-(4-氨基苯(甲)酰)-L-谷氨酸二乙酯合成路线 （共 22 条）
反应条件
1: 11 percent / CaCO3 / dimethylformamide / 17 h / 135 °C
2: 46 percent / CaCO3 / N,N-dimethyl-acetamide / 45 h / 25 °C
3: 60 percent / aq. NaOH / ethanol / 2 h / Ambient temperature
View Scheme
参考文献
Jones, Terence R.; Calvert, A. Hilary; Jackman, Ann L.; Eakin, M. Allan; Smithers, Michael J.; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1468 - 1476
参考文献
Loriga; Piras; Sanna; Paglietti
Farmaco, 1997 , vol. 52, # 3 p. 157 - 166
