1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -20 °C / Inert atmosphere 2: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 0.33 h / 0 °C / Inert atmosphere 3: boron trifluoride diethyl etherate / acetonitrile / 0.5 h / 0 °C / Inert atmosphere 4: 30 Pd/C; hydrogen / tetrahydrofuran; methanol / 3 h / 20 °C / 760.05 Torr / Inert atmosphere 5: pyridine; 4-(N,N-dimethlyamino)pyridine / 5.5 h / 20 °C / Inert atmosphere 6: triphenylphosphine hydrobromide / acetonitrile / 5 h / 0 - 55 °C / Inert atmosphere 7: copper(I) bromide / dichloromethane / 3 h / Reflux; Inert atmosphere 8: sulfuric acid; acetic acid / 12 h / 0 - 20 °C / Inert atmosphere 9: trimethylsilylazide / tert-butyl alcohol / 10 h / Reflux; Inert atmosphere 10: hydrogen / ethanol / 15 h / 20 °C / 760.05 Torr / Inert atmosphere 11: tetrahydrofuran / 29 h / 50 °C / Inert atmosphere 12: methanol; sodium methylate / 1 h / 20 °C / Inert atmosphere 13: trifluoroacetic acid / dichloromethane / 2.5 h / 20 °C / Inert atmosphere View Scheme

1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -20 °C / Inert atmosphere 2: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 0.33 h / 0 °C / Inert atmosphere 3: boron trifluoride diethyl etherate / acetonitrile / 0.5 h / 0 °C / Inert atmosphere 4: 30 Pd/C; hydrogen / tetrahydrofuran; methanol / 3 h / 20 °C / 760.05 Torr / Inert atmosphere 5: pyridine; 4-(N,N-dimethlyamino)pyridine / 5.5 h / 20 °C / Inert atmosphere 6: triphenylphosphine hydrobromide / acetonitrile / 5 h / 0 - 55 °C / Inert atmosphere 7: copper(I) bromide / dichloromethane / 3 h / Reflux; Inert atmosphere 8: sulfuric acid; acetic acid / 12 h / 0 - 20 °C / Inert atmosphere 9: trimethylsilylazide / tert-butyl alcohol / 10 h / Reflux; Inert atmosphere View Scheme

1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -20 °C / Inert atmosphere 2: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 0.33 h / 0 °C / Inert atmosphere 3: boron trifluoride diethyl etherate / acetonitrile / 0.5 h / 0 °C / Inert atmosphere 4: 30 Pd/C; hydrogen / tetrahydrofuran; methanol / 3 h / 20 °C / 760.05 Torr / Inert atmosphere 5: pyridine; 4-(N,N-dimethlyamino)pyridine / 5.5 h / 20 °C / Inert atmosphere 6: triphenylphosphine hydrobromide / acetonitrile / 5 h / 0 - 55 °C / Inert atmosphere 7: copper(I) bromide / dichloromethane / 3 h / Reflux; Inert atmosphere 8: sulfuric acid; acetic acid / 12 h / 0 - 20 °C / Inert atmosphere 9: trimethylsilylazide / tert-butyl alcohol / 10 h / Reflux; Inert atmosphere 10: hydrogen / ethanol / 15 h / 20 °C / 760.05 Torr / Inert atmosphere View Scheme

1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -20 °C / Inert atmosphere 2: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 0.33 h / 0 °C / Inert atmosphere 3: boron trifluoride diethyl etherate / acetonitrile / 0.5 h / 0 °C / Inert atmosphere 4: 30 Pd/C; hydrogen / tetrahydrofuran; methanol / 3 h / 20 °C / 760.05 Torr / Inert atmosphere 5: pyridine; 4-(N,N-dimethlyamino)pyridine / 5.5 h / 20 °C / Inert atmosphere 6: triphenylphosphine hydrobromide / acetonitrile / 5 h / 0 - 55 °C / Inert atmosphere 7: copper(I) bromide / dichloromethane / 3 h / Reflux; Inert atmosphere 8: sulfuric acid; acetic acid / 12 h / 0 - 20 °C / Inert atmosphere View Scheme