2,5-二甲基苯甲酸甲酯合成路线 （共 14 条）
反应条件
magnesium 1.) ether, 2.) ether, reflux, 2 h; room temp., overnight; Yield given. Multistep reaction;
参考文献
Neudeck
Monatshefte fur Chemie, 1996 , vol. 127, # 2 p. 185 - 200
反应条件
silica gel; zinc(II) chloride T=70°C; 0.416667 h; Irradiation; Product distribution; Further Variations:ReagentsReaction partners;
参考文献
Fraile, Jose M.; Garcia, Jose I.; Gomez, Maria A.; De La Hoz, Antonio; Mayoral, Jose A.; Moreno, Andres; Prieto, Pilar; Salvatella, Luis; Vazquez, Ester
European Journal of Organic Chemistry, 2001 , # 15 p. 2891 - 2899
参考文献
Budesinsky, Milos; Kulhanek, Jiri; Boehm, Stanislav; Cigler, Petr; Exner, Otto
Magnetic Resonance in Chemistry, 2004 , vol. 42, # 10 p. 844 - 851
反应条件
1: sulfuric acid; nitric acid / 0.33 h / 0 °C
2: diisobutylaluminium hydride / tetrahydrofuran; toluene / 1 h / -78 °C
View Scheme
参考文献
VITAS PHARMA RESEARCH PVT LTD; ALAPATI, Chandrasekhar; BANERJEE, Ankita; RANGARAJAN, Radha; KUMAR, Rajinder
Patent: WO2014/57415 A2, 2014 ;
