1-苯基-1-三甲基甲硅氧基乙烯合成路线 （共 431 条）
反应条件
1: (Ra)-BINOL-(O-)2P-N-c-C12-N-(R)-(2-MeO-PhCH-Me); [(COD)IrCl]2; CsF / ZnF2; propylamine / tetrahydrofuran; bis-(2-methoxy-ethyl) ether / 18 h / 50 °C
2: 74 mg / [(PPh3)3RhCl]; H2 / tetrahydrofuran / 9 h / 20 °C / 750.06 Torr
View Scheme
参考文献
Graening, Timm; Hartwig, John F.
Journal of the American Chemical Society, 2005 , vol. 127, # 49 p. 17192 - 17193
反应条件
trityl chloride; tin(ll) chloride in dichloromethane
T=-78°C; 1.66667 h;
参考文献
Mukaiyama, Teruaki; Kobayashi, Shu
Journal of Organometallic Chemistry, 1990 , vol. 382, # 1-2 p. 39 - 52
反应条件
1: With n-butyllithium; zirconocene dichloride in tetrahydrofuran; hexane
T=-78°C; 1 h;
2: With water-d2 in tetrahydrofuran
2 h; Heating;
参考文献
Ganchegui; Bertus; Szymoniak
Synlett, 2001 , # 1 p. 123 - 125
反应条件
zinc trifluoromethanesulfonate; 1-azido-3,3-dimethyl-3-(1H)-1,2-benziodoxole in toluene
T=20°C; 12 h; Inert atmosphere;
参考文献
Vita, Maria Victoria; Waser, Jerome
Organic Letters, 2013 , vol. 15, # 13 p. 3246 - 3249
反应条件
1: 80 percent / CHCl3 / 5 h / Ambient temperature
2: Et3N / CHCl3 / 24 h / Ambient temperature
View Scheme
参考文献
Sasaki, Tadashi; Ishibashi, Yukio; Ohno, Masatomi
Chemistry Letters, 1983 , p. 863 - 866
反应条件
tin(IV) chloride; zinc(II) chloride in dichloromethane
T=-78°C; 2 h;
参考文献
Hayashi, Masaji; Inubushi, Atsuro; Mukaiyama, Teruaki
Bulletin of the Chemical Society of Japan, 1988 , vol. 61, # 11 p. 4037 - 4042
反应条件
1: With trifluorormethanesulfonic acid in acetonitrile
T=20°C; 3 h;
2: With manganese triacetate in acetic acid; acetonitrile
T=20°C; 24 h;
参考文献
Akiyama, Takahiko; Nakashima, Saeko; Yokota, Koji; Fuchibe, Kohei
Chemistry Letters, 2004 , vol. 33, # 7 p. 922 - 923
反应条件
1: 92 percent / dioxane / 5 h / 25 °C
2: 65 percent / Zn dust / acetic acid / 9 h / 25 °C
3: NaOH / tetrahydrofuran / Heating
4: Cu powder / quinoline / 200 °C
View Scheme
参考文献
Boger, Dale L.; Coleman, Robert S.; Panek, James S.; Yohannes, Daniel
Journal of Organic Chemistry, 1984 , vol. 49, # 23 p. 4405 - 4409
反应条件
1: With 2,3,5,5-tetramethyl-5-sila-2-oxazolinium tetrakis[3,5-bis-(trifluoromethyl)phenyl]borate in dichloromethane
T=20°C; 10 h; Inert atmosphereSchlenk technique;
2: With ammonium chloride in dichloromethane
Inert atmosphereSchlenk technique;
参考文献
Chandra Sheker Reddy, Anugu; Chen, Zhang; Hatanaka, Tohru; Minami, Tatsuya; Hatanaka, Yasuo
Organometallics, 2013 , vol. 32, # 13 p. 3575 - 3582
反应条件
boron trifluoride diethyl etherate in dichloromethane
T=20°C; Friedel-Crafts type alkylation; 4 h;
参考文献
Aoyama, Motoshi; Hara, Shoji
Tetrahedron, 2009 , vol. 65, # 18 p. 3682 - 3687
